- Sandwich Shop Restaurants, Ripley
- Satellite Dish Antennas & Equipment Dealers, Ripley
- Satellite TV Service, Ripley
- Scrap & Waste Machinery, Ripley
- Scrap & Waste Materials, Ripley
- Secondary Schools, Ripley
- Security Brokers & Dealers, Ripley
- Seeds & Bulbs Wholesale & Growers, Ripley
- Septic Tank Pumping & Cleaning, Ripley - Septic Systems
- Shoe Stores, Ripley - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Ripley
- Small Business & Office Equipment Repair Services, Ripley
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- Snacks & Desserts, Ripley
- Social Services & Welfare, Ripley
- Specialty Stores, Ripley
- Sporting Goods Stores, Ripley
- Staffing & Support Services, Ripley
- State Government, Ripley
- Steak House Restaurants, Ripley
- Stocks & Bond Brokers, Ripley
- Surplus & Salvage Merchandise, Ripley
- Surveyor Services, Ripley - Surveying Service
- Surveyors, Ripley
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