- Safety Shoes, Jamestown
- Salvage Yards, Jamestown - Auto, Motorcycle, Boat, Trucks, etc
- Sandwich Shop Restaurants, Jamestown
- Satellite TV Service, Jamestown
- Savings & Loan Associations, Jamestown
- Savings Banks, Jamestown
- Sawmill & Planing Mills, Jamestown
- Sawmill Supplies & Equipment Repair, Jamestown
- Senior Citizens Service & Health Organizations, Jamestown
- Septic & Cesspool Equipment & Supplies, Jamestown
- Septic Tank Pumping & Cleaning, Jamestown - Septic Systems
- Septic Tanks & Systems, Jamestown - Wholesale, Dealers & Suppliers
- Sewing & Yarn Stores & Supplies, Jamestown
- Shoe Store - More, Jamestown
- Shoe Stores, Jamestown - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Jamestown
- Sitting Services, Jamestown
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- Skating Rink & Hockey Operation Services, Jamestown
- Social Clubs & Organizations, Jamestown
- Social Security And Disability Attorneys & Lawyers, Jamestown
- Social Security And Disability Lawyers & Attorneys, Jamestown
- Social Services & Welfare, Jamestown
- Specialty Animal Services, Jamestown
- Specialty Stores, Jamestown
- Sporting Goods Stores, Jamestown
- Sports & Recreational Services, Jamestown
- Sportswear Manufacturers, Jamestown
- Sportswear Wholesale, Jamestown
- State Government, Jamestown
- Stone, Jamestown
- Stoves & Furnace Equipment, Jamestown - Fittings & Repair Parts
- Substance Abuse Clinics, Jamestown - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Surveyor Services, Jamestown - Surveying Service
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